Structure of PDB 5cg9 Chain D Binding Site BS02
Receptor Information
>5cg9 Chain D (length=264) Species:
5762
(Naegleria gruberi) [
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INKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGS
VELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTA
DLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNC
LYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELT
DKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYY
EDTQKNSLKIHKET
Ligand information
>5cg9 Chain F (length=13) [
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tgtcagcgcatgg
Receptor-Ligand Complex Structure
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PDB
5cg9
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Resolution
2.693 Å
Binding residue
(original residue number in PDB)
Y141 Y153 T155 A156 R224 D234 V293 F295 H297 Q310
Binding residue
(residue number reindexed from 1)
Y85 Y97 T99 A100 R168 D178 V237 F239 H241 Q254
Enzymatic activity
Enzyme Commision number
1.14.11.80
: methylcytosine dioxygenase.
External links
PDB
RCSB:5cg9
,
PDBe:5cg9
,
PDBj:5cg9
PDBsum
5cg9
PubMed
26323320
UniProt
D2W6T1
|TET1_NAEGR Tet-like dioxygenase 1 (Gene Name=TET1)
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