Structure of PDB 4wce Chain D Binding Site BS02

Receptor Information

>4wce Chain D (length=166) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAV
EELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLI
SVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDI
VIVTTANTDEEARELL

Ligand information

>4wce Chain Y (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ucuggugacuauagcaaggaggucacaccuguucccaugccgaacacaga
aguuaaggucuuuagcgacgaugguagccaacuuacguuccgcuagagua
gaacguugccaggc

.<<.<..<.....<<<<<<<......<<<<<...............>>>.
.>>.....>>>>>.>><.........<.<............>.>......
...>..>..>.>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wce Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
Resolution	3.526 Å
Binding residue (original residue number in PDB)	S24 M26 E27 T61 Q63
Binding residue (residue number reindexed from 1)	S20 M22 E23 T57 Q59

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:4wce, PDBe:4wce, PDBj:4wce
PDBsum	4wce
PubMed	26464510
UniProt	Q2FW18\|RL5_STAA8 Large ribosomal subunit protein uL5 (Gene Name=rplE)

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