Structure of PDB 4ue5 Chain D Binding Site BS02

Receptor Information

>4ue5 Chain D (length=433) Species: 9615 (Canis lupus familiaris)

MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVK
QLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGK
QNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQ
NATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDS
LFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKL
DGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDI
EGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILG
MIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQP
GRIQRVARGSGVSTRDVQELLTQYTKFAQMVKK

Ligand information

>4ue5 Chain S (length=18) Species: 9615 (Canis lupus familiaris)

LGFPINFLTLYVTVQHKK

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4ue5 Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
• Resolution: 9.0 Å
• Binding residue (original residue number in PDB): M351 I352
• Binding residue (residue number reindexed from 1): M351 I352

Enzymatic activity

• Enzyme Commision number: 3.6.5.4: signal-recognition-particle GTPase.

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0008312 7S RNA binding
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006614 SRP-dependent cotranslational protein targeting to membrane

Cellular Component

• GO:0048500 signal recognition particle

External links

• PDB: RCSB:4ue5, PDBe:4ue5, PDBj:4ue5
• PDBsum: 4ue5
• PubMed: 26344568
• UniProt: P61010|SRP54_CANLF Signal recognition particle subunit SRP54 (Gene Name=SRP54)