Structure of PDB 4tky Chain D Binding Site BS02

Receptor Information
>4tky Chain D (length=189) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHAYQFEEVLHISDNVKKKL
PEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQ
TIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGV
PAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
Ligand information
Receptor-Ligand Complex Structure
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PDB4tky Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
C30 H32 F63 M64 R148 G149 V150 P163 Q164 F174
Binding residue
(residue number reindexed from 1)
C30 H32 F63 M64 R148 G149 V150 P163 Q164 F174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003756 protein disulfide isomerase activity
GO:0005515 protein binding
GO:0015035 protein-disulfide reductase activity
GO:0015036 disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0071236 cellular response to antibiotic
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Biological Process

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Cellular Component
External links
PDB RCSB:4tky, PDBe:4tky, PDBj:4tky
PDBsum4tky
PubMed25470204
UniProtP0AEG4|DSBA_ECOLI Thiol:disulfide interchange protein DsbA (Gene Name=dsbA)

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