Structure of PDB 4p3w Chain D Binding Site BS02

Receptor Information
>4p3w Chain D (length=162) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHCDLSLKIPQDMTAQVTSPSGKTHEAEIHTYCIRFVPAEMGTHTVSVKY
KGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREA
GAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHI
PDSPFVVPVASP
Ligand information
Receptor-Ligand Complex Structure
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PDB4p3w Crystal structure of the human filamin A Ig-like domains 20-21 in complex with migfilin peptide
Resolution2.0 Å
Binding residue
(original residue number in PDB)
G2223 P2225 F2226 Q2227 F2228 T2229 E2313 E2314 H2315
Binding residue
(residue number reindexed from 1)
G57 P59 F60 Q61 F62 T63 E147 E148 H149
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization

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Molecular Function

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Biological Process
External links
PDB RCSB:4p3w, PDBe:4p3w, PDBj:4p3w
PDBsum4p3w
PubMed
UniProtP21333|FLNA_HUMAN Filamin-A (Gene Name=FLNA)

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