Structure of PDB 4m6b Chain D Binding Site BS02

Receptor Information
>4m6b Chain D (length=187) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAA
YNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQAQSSSA
RAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGN
AAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGG
Ligand information
>4m6b Chain F (length=23) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SVGLSALFDLDLDDSEDFTVNSS
Receptor-Ligand Complex Structure
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PDB4m6b The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer.
Resolution1.78 Å
Binding residue
(original residue number in PDB)
K37 S41 Y45 I57 S58 Q59 K60 M62 S63 I64 S67 R194 P197 R198 Q201 R205 I214 R215 I218
Binding residue
(residue number reindexed from 1)
K2 S6 Y10 I22 S23 Q24 K25 M27 S28 I29 S32 R159 P162 R163 Q166 R170 I179 R180 I183
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:4m6b, PDBe:4m6b, PDBj:4m6b
PDBsum4m6b
PubMed24507717
UniProtP02293|H2B1_YEAST Histone H2B.1 (Gene Name=HTB1);
Q12692

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