Structure of PDB 4it5 Chain D Binding Site BS02

Receptor Information
>4it5 Chain D (length=169) Species: 666 (Vibrio cholerae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYFELFGLPIQFELDGSLLSSQFRALQKRFHPDNFATASERDRLMAVQQA
AQINDAYQTLKDPLRRAEYLLSLQGIEMNAEQQTLQDPMFLMEQMELREE
LESVTACADPEAALVAFDTKVTAMQRHYLAQLQGQLAQSEWLAAADQIRK
LKFIAKLKNEVERVEDQLL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4it5 Chain D Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4it5 Chaperone HscB from Vibrio cholerae.
Resolution2.152 Å
Binding residue
(original residue number in PDB)		E163 E166
Binding residue
(residue number reindexed from 1)		E162 E165
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001671 ATPase activator activity
GO:0051087 protein-folding chaperone binding
Biological Process
GO:0006457 protein folding
GO:0044571 [2Fe-2S] cluster assembly
GO:0051259 protein complex oligomerization
GO:0097428 protein maturation by iron-sulfur cluster transfer
Cellular Component
GO:1990230 iron-sulfur cluster transfer complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4it5, PDBe:4it5, PDBj:4it5
PDBsum4it5
PubMed
UniProtQ9KTX9|HSCB_VIBCH Co-chaperone protein HscB homolog (Gene Name=hscB)

[Back to BioLiP]