Structure of PDB 4ibu Chain D Binding Site BS02

Receptor Information
>4ibu Chain D (length=196) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQ
LWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHL
IRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMG
GMNRRPILTIITLEDSSGNLLGRNSFEVCVCACPGRDRRREEENLR
Ligand information
Receptor-Ligand Complex Structure
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PDB4ibu Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		S241 C275 A276 C277 R280 R284
Binding residue
(residue number reindexed from 1)		S147 C181 A182 C183 R186 R190
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ibu, PDBe:4ibu, PDBj:4ibu
PDBsum4ibu
PubMed23863845
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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