Structure of PDB 4gbc Chain D Binding Site BS02

Receptor Information
>4gbc Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTDKT
Ligand information
>4gbc Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB4gbc A T3R3 hexamer of the human insulin variant B28Asp.
Resolution1.778 Å
Binding residue
(original residue number in PDB)
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30
Binding residue
(residue number reindexed from 1)
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:4gbc, PDBe:4gbc, PDBj:4gbc
PDBsum4gbc
PubMed23428413
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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