Structure of PDB 4cy7 Chain D Binding Site BS02

Receptor Information
>4cy7 Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCASHLVEALYLVCGERGFFYTPKT
Ligand information
>4cy7 Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB4cy7 An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Resolution1.4 Å
Binding residue
(original residue number in PDB)
Q4 H5 L6 C7 L11 L15 V18 C19 G23 F24 T30
Binding residue
(residue number reindexed from 1)
Q4 H5 L6 C7 L11 L15 V18 C19 G23 F24 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:4cy7, PDBe:4cy7, PDBj:4cy7
PDBsum4cy7
PubMed24819248
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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