Structure of PDB 4a0k Chain D Binding Site BS02

Receptor Information

>4a0k Chain D (length=355) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GQTSILHYIYKSSLGQSIHAQLRQCLQEPFIRSLKSYKLHRTASPFDRRV
TSLEWHPTHPTTVAVGSKGGDIILWDYDVQNKTSFIQGMGPGDAITGMKF
NQFNTNQLFVSSIRGATTLRDFSGSVIQVFAKTDSWDYWYCCVDVSVSRQ
MLATGDSTGRLLLLGLDGHEIFKEKLHKAKVTHAEFNPRCDWLMATSSVD
ATVKLWDLRNIKDKNSYIAEMPHEKPVNAAYFNPTDSTKLLTTDQRNEIR
VYSSYDWSKPDQIIIHPHRQFQHLTPIKATWHPMYDLIVAGRYPDDQLLL
NDKRTIDIYDANSGGLVHQLRDPNAAGIISLNKFSPTGDVLASGMGFNIL
IWNRE

Ligand information

>4a0k Chain F (length=12) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tgcgtaagtagc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4a0k The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Resolution	5.93 Å
Binding residue (original residue number in PDB)	R369 F371 Q372 H373 Y393 R404 G427 I428 F447
Binding residue (residue number reindexed from 1)	R269 F271 Q272 H273 Y293 R304 G327 I328 F347

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003684	damaged DNA binding

	Biological Process
GO:0006281	DNA repair

	Cellular Component
GO:0005634	nucleus
GO:0080008	Cul4-RING E3 ubiquitin ligase complex

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External links

PDB	RCSB:4a0k, PDBe:4a0k, PDBj:4a0k
PDBsum	4a0k
PubMed	22118460
UniProt	Q2YDS1\|DDB2_DANRE DNA damage-binding protein 2 (Gene Name=ddb2)

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