Structure of PDB 3spl Chain D Binding Site BS02

Receptor Information
>3spl Chain D (length=200) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLT
HVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANY
IKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTS
NLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3spl Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
Resolution2.101 Å
Binding residue
(original residue number in PDB)		F34 F65 K67 S142 A164 H165 F194
Binding residue
(residue number reindexed from 1)		F2 F33 K35 S110 A132 H133 F162
Enzymatic activity
Enzyme Commision number 3.6.1.71: adenosine-5'-diphospho-5'-[DNA] diphosphatase.
3.6.1.72: DNA-3'-diphospho-5'-guanosine diphosphatase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:3spl, PDBe:3spl, PDBj:3spl
PDBsum3spl
PubMed21984208
UniProtO74859|APTX_SCHPO Aprataxin-like protein (Gene Name=hnt3)

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