Structure of PDB 3s29 Chain D Binding Site BS02

Receptor Information
>3s29 Chain D (length=781) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEVLALLSRVEAKGKGILQQNQIIAEFEALPEQTRKKLEGGPFFDLLKST
QEAIVLPPWVALAVRPRPGVWEYLRVNLHALVVEELQPAEFLHFKEELVD
GVKNGNFTLELDFEPFNASIPRPTLHKYIGNGVDFLNRHLSAKLFHDKES
LLPLLKFLRLHSHQGKNLMLSEKIQNLNTLQHTLRKAEEYLAELKSETLY
EEFEAKFEEIGLERGWGDNAERVLDMIRLLLDLLEAPDPCTLETFLGRVP
MVFNVVILSPHGYFAQDNVLGYPDTGGQVVYILDQVRALEIEMLQRIKQQ
GLNIKPRILILTRLLPDAVGTTCGERLERVYDSEYCDILRVPFRTEKGIV
RKWISRFEVWPYLETYTEDAAVELSKELNGKPDLIIGNYSDGNLVASLLA
HKLGVTQCTIAHALEKTKYPDSDIYWKKLDDKYHFSCQFTADIFAMNHTD
FIITSTFQEIAGSKETVGQYESHTAFTLPGLYRVVHGIDVFDPKFNIVSP
GADMSIYFPYTEEKRRLTKFHSEIEELLYSDVENKEHLCVLKDKKKPILF
TMARLDRVKNLSGLVEWYGKNTRLRELANLVVVGGDRRKESKDNEEKAEM
KKMYDLIEEYKLNGQFRWISSQMDRVRNGELYRYICDTKGAFVQPALYEA
FGLTVVEAMTCGLPTFATCKGGPAEIIVHGKSGFHIDPYHGDQAADTLAD
FFTKCKEDPSHWDEISKGGLQRIEEKYTWQIYSQRLLTLTGVYGFWKHVS
NLDRLEARRYLEMFYALKYRPLAQAVPLAQD
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain3s29 Chain D Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3s29 The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		H287 D300 G302 Q304 R382 A439
Binding residue
(residue number reindexed from 1)		H261 D274 G276 Q278 R356 A413
Annotation score5
Enzymatic activity
Enzyme Commision number 2.4.1.13: sucrose synthase.
Gene Ontology
Molecular Function
GO:0016157 sucrose synthase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0001666 response to hypoxia
GO:0005985 sucrose metabolic process
GO:0006970 response to osmotic stress
GO:0009409 response to cold
GO:0009413 response to flooding
GO:0009414 response to water deprivation
GO:0009744 response to sucrose
GO:0009749 response to glucose
GO:0010555 response to mannitol
GO:0071456 cellular response to hypoxia
GO:0072708 response to sorbitol
Cellular Component
GO:0005829 cytosol
GO:0009506 plasmodesma

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s29, PDBe:3s29, PDBj:3s29
PDBsum3s29
PubMed21865170
UniProtP49040|SUS1_ARATH Sucrose synthase 1 (Gene Name=SUS1)

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