Structure of PDB 3gqc Chain D Binding Site BS02

Receptor Information

>3gqc Chain D (length=433) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

CNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLQSCIMH
VDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQ
NANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFH
AYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAV
RMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQ
LVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRF
CRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLE
ATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNAK
IIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPT

Ligand information

>3gqc Chain K (length=12) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

atcctcccctac

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3gqc Structure of the human Rev1-DNA-dNTP ternary complex.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	I361 S568 E571 P650 G651 G653 S655 M656 R752 T783
Binding residue (residue number reindexed from 1)	I16 S174 E177 P256 G257 G259 S261 M262 R358 T389

Enzymatic activity

Enzyme Commision number

2.7.7.-

Gene Ontology

	Molecular Function
GO:0003684	damaged DNA binding
GO:0003887	DNA-directed DNA polymerase activity

	Biological Process
GO:0006281	DNA repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:3gqc, PDBe:3gqc, PDBj:3gqc
PDBsum	3gqc
PubMed	19464298
UniProt	Q9UBZ9\|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)

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