Structure of PDB 3ere Chain D Binding Site BS02

Receptor Information
>3ere Chain D (length=156) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELG
AVKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNL
AVLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAG
MFENLR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ere Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		S36 Q37 Q53 A54 S57 R58 K67 Y78
Binding residue
(residue number reindexed from 1)		S22 Q23 Q39 A40 S43 R44 K53 Y64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0034618 arginine binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0051259 protein complex oligomerization
GO:1900079 regulation of arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ere, PDBe:3ere, PDBj:3ere
PDBsum3ere
PubMed18952097
UniProtP9WPY9|ARGR_MYCTU Arginine repressor (Gene Name=argR)

[Back to BioLiP]