Structure of PDB 3clz Chain D Binding Site BS02
Receptor Information
>3clz Chain D (length=209) Species:
9606
(Homo sapiens) [
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NHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGG
YEDDVDHGNFFTYTGSGGRDLSGNKRTAEQSCDQKLTNTNRALALNCFAP
INDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYW
PEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEAL
ANAHHHHHH
Ligand information
>3clz Chain L (length=12) [
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ccctgcgggccc
Receptor-Ligand Complex Structure
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PDB
3clz
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
R452 S453 N489 R491
Binding residue
(residue number reindexed from 1)
R37 S38 N74 R76
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3clz
,
PDBe:3clz
,
PDBj:3clz
PDBsum
3clz
PubMed
18772889
UniProt
Q96T88
|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)
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