Structure of PDB 2x2f Chain D Binding Site BS02

Receptor Information
>2x2f Chain D (length=333) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFSMEDLIPLVNRLQDAFSADLDLPQIAVVGGQSAGKSSVLENFVGRDFL
PRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDR
VTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIR
DMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKL
DLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERK
FFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSI
EKEVEEYKNFSRVDEMLRMYHALKEALSIIGNI
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain2x2f Chain D Residue 1747 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2x2f G Domain Dimerization Controls Dynamin'S Assembly-Stimulated Gtpase Activity.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q40 S41 K44 V64 T65 G139
Binding residue
(residue number reindexed from 1)		Q33 S34 K37 V57 T58 G132
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2x2f, PDBe:2x2f, PDBj:2x2f
PDBsum2x2f
PubMed20428113
UniProtQ05193|DYN1_HUMAN Dynamin-1 (Gene Name=DNM1)

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