Structure of PDB 2v3c Chain D Binding Site BS02

Receptor Information
>2v3c Chain D (length=401) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKLGENLNKALNKLKAAAFVDKKLIKEVIKDIQRALIQADVNVKLVLKM
SKEIERRALEEKTPKGLSKKEHIIKIVYEELVKLLGEEAKKLELNPKKQN
VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAAYEQLKQLA
EKIHVPIYGDETRTKSPVDIVKEGMEKFKKADVLIIDTAGRHKEEKGLLE
EMKQIKEITNPDEIILVIDGTIGQQAGIQAKAFKEAVGEIGSIIVTKLDG
SAKGGGALSAVAETKAPIKFIGIGEGIDDLEPFDPKKFISRLLGMGDLES
LLEKAEDMVDEKTEESIDAIMRGKFTLNELMTQLEAIELTEAKIKKYKVI
ISSMTKEERENPKIIKASRIRRIARGSGTTENDVREVLRYYETTKNAIDK
L
Ligand information
>2v3c Chain N (length=96) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcggugggggagcaucuccuguaggggagauguaacccccuuuaccugc
cgaaccccgccaggcccggaagggagcaacgguaggcaggacgucg
.<<<..<<<<<.<<<<<<<<<....>>>>>>>>>..>>>>>....<<<<<
<.....<<<.....<<<....>>>.....>>>..>>>>>>.>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2v3c Interaction of Signal-Recognition Particle 54 Gtpase Domain and Signal-Recognition Particle RNA in the Free Signal-Recognition Particle.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K305 K371 V375 S378 S379 M380 T381 K382 S394 R395 R398 G402 S403
Binding residue
(residue number reindexed from 1)		K304 K345 V349 S352 S353 M354 T355 K356 S368 R369 R372 G376 S377
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0060090 molecular adaptor activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0048500 signal recognition particle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2v3c, PDBe:2v3c, PDBj:2v3c
PDBsum2v3c
PubMed17846429
UniProtQ57565|SRP54_METJA Signal recognition particle 54 kDa protein (Gene Name=srp54)

[Back to BioLiP]