Structure of PDB 2rex Chain D Binding Site BS02

Receptor Information
>2rex Chain D (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET
EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVALKKWR
TEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQ
LGAEIYLEGSAFTSEKSIHSIFRTASMLCL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2rex Chain D Residue 551 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2rex Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y38 E40
Binding residue
(residue number reindexed from 1)		Y32 E34
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:2rex, PDBe:2rex, PDBj:2rex
PDBsum2rex
PubMed
UniProtQ92730|RND1_HUMAN Rho-related GTP-binding protein Rho6 (Gene Name=RND1)

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