Structure of PDB 2r35 Chain D Binding Site BS02

Receptor Information
>2r35 Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>2r35 Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB2r35 Metal induced structural changes observed in hexameric insulin
Resolution2.08 Å
Binding residue
(original residue number in PDB)		F1 N3 H5 C7 L15 V18 C19 R22 G23 F24 F25 Y26 T27 T30
Binding residue
(residue number reindexed from 1)		F1 N3 H5 C7 L15 V18 C19 R22 G23 F24 F25 Y26 T27 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2r35, PDBe:2r35, PDBj:2r35
PDBsum2r35
PubMed18977386
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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