Structure of PDB 2p5g Chain D Binding Site BS02

Receptor Information
>2p5g Chain D (length=875) Species: 12353 (Escherichia phage RB69) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYFD
IYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYEI
KYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFDL
LNSPYGNVEEWSIEIAAGGDEVPSEIIDKIIYMPFDNEKELLMEYLNFWQ
QKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRVKVIENM
YGSREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNVGKLKYD
GPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYYAKIQIQ
SVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPIPNRYKY
VMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERPSDVYSC
SPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNGEIIKEAPLDV
DYRFDDEIKEKIKKLSAKSLNEMLFRAQRTEVAGMTAQINRKLLINSLYG
ALGNVWFRYYDLRNATAITTFGQMALQWIERKVNEYLNEVCGTEGEAFVL
YGDTDSIYVSADKIIDKVGESKFRDTNHWVDFLDKFARERMEPAIDRGFR
EMCEYMNNKQHLMFMDREAIAGPPLGSKGIGGFWTGKKRYALNVWDMEGT
RYAEPKLKIMGLETQKSSTPKAVQKALKECIRRMLQEGEESLQEYFKEFE
KEFRQLNYISIASVSSANNIAKYDVGGFPGPKCPFHIRGILTYNRAIPQV
VEGEKVYVLPLREGNPFGDKCIAWPSGTEITDLIKDDVLHWMDYTVLLEK
TFIKPLEGFTSAAKLDYEKKASLFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2p5g Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q733 S735 S783 S784 N786 H804
Binding residue
(residue number reindexed from 1)		Q715 S717 S765 S766 N768 H786
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2p5g, PDBe:2p5g, PDBj:2p5g
PDBsum2p5g
PubMed17718515
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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