Structure of PDB 2ixp Chain D Binding Site BS02

Receptor Information

>2ixp Chain D (length=310) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISH
CSDPDPHATASSIAMVNGLMGVLDKLAHLIDETPPLGNLACREWHHKLDE
RLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVA
ALDMLGMFPHMRGADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDH
FHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINE
VKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWF
GTGFFPWVNI

Ligand information

>2ixp Chain I (length=6) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cAAPKc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2ixp Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	K298 F299 P300
Binding residue (residue number reindexed from 1)	K291 F292 P293

Enzymatic activity

Enzyme Commision number

5.2.1.8: peptidylprolyl isomerase.

Gene Ontology

	Molecular Function
GO:0019211	phosphatase activator activity

View graph for
Molecular Function

External links

PDB	RCSB:2ixp, PDBe:2ixp, PDBj:2ixp
PDBsum	2ixp
PubMed	16885030
UniProt	P40454\|PTPA1_YEAST Serine/threonine-protein phosphatase 2A activator 1 (Gene Name=RRD1)

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