Structure of PDB 2hnv Chain D Binding Site BS02
Receptor Information
>2hnv Chain D (length=81) Species:
9913
(Bos taurus) [
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VRTCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQS
GVKPCGSGGRCAAAGICCSPDGCHEDPACDP
Ligand information
Ligand ID
TYR
InChI
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChIKey
OUYCCCASQSFEME-QMMMGPOBSA-N
SMILES
Software
SMILES
ACDLabs 10.04
O=C(O)C(N)Cc1ccc(O)cc1
OpenEye OEToolkits 1.5.0
c1cc(ccc1C[C@@H](C(=O)O)N)O
OpenEye OEToolkits 1.5.0
c1cc(ccc1CC(C(=O)O)N)O
CACTVS 3.341
N[CH](Cc1ccc(O)cc1)C(O)=O
CACTVS 3.341
N[C@@H](Cc1ccc(O)cc1)C(O)=O
Formula
C9 H11 N O3
Name
TYROSINE
ChEMBL
CHEMBL925
DrugBank
DB00135
ZINC
ZINC000000266964
PDB chain
2hnv Chain D Residue 2 [
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Receptor-Ligand Complex Structure
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PDB
2hnv
Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: crystal structures and mutation studies of bovine neurophysin-I.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
C10 C21 G23 P24 C44 E47 C54
Binding residue
(residue number reindexed from 1)
C4 C15 G17 P18 C38 E41 C48
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005185
neurohypophyseal hormone activity
Cellular Component
GO:0005576
extracellular region
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Molecular Function
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Cellular Component
External links
PDB
RCSB:2hnv
,
PDBe:2hnv
,
PDBj:2hnv
PDBsum
2hnv
PubMed
17192588
UniProt
P01175
|NEU1_BOVIN Oxytocin-neurophysin 1 (Gene Name=OXT)
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