Structure of PDB 2g2p Chain D Binding Site BS02

Receptor Information
>2g2p Chain D (length=112) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALW
PEQTATTGDYRVVFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLL
LSQYGYSTYRGS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2g2p Chain D Residue 1008 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2g2p The transthyretin-related protein: structural investigation of a novel protein family
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H96 H98 S114
Binding residue
(residue number reindexed from 1)		H94 H96 S112
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.2.17: hydroxyisourate hydrolase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0033971 hydroxyisourate hydrolase activity
GO:0042802 identical protein binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0051289 protein homotetramerization
Cellular Component
GO:0032991 protein-containing complex
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2g2p, PDBe:2g2p, PDBj:2g2p
PDBsum2g2p
PubMed16723258
UniProtP76341|HIUH_ECOLI 5-hydroxyisourate hydrolase (Gene Name=hiuH)

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