Structure of PDB 2c20 Chain D Binding Site BS02

Receptor Information
>2c20 Chain D (length=329) Species: 198094 (Bacillus anthracis str. Ames) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNG
DLRDKAFLRDVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCL
LEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEK
MLHWYSQASNLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALG
QREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKDLQNGGESDFYN
LGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKL
GWDPRYVNVKTIIEHAWNWHQKQPNGYEK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2c20 Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2c20 Crystal Structure of Udp-Glucose 4-Epimerase from Bacillus Anthracis at 2.7A Resolution
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E183 H185 E188 H190
Binding residue
(residue number reindexed from 1)		E182 H184 E187 H189
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) T118 A119 A120 Y142 K146 H185
Catalytic site (residue number reindexed from 1) T117 A118 A119 Y141 K145 H184
Enzyme Commision number 5.1.3.2: UDP-glucose 4-epimerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003978 UDP-glucose 4-epimerase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006012 galactose metabolic process
GO:0033499 galactose catabolic process via UDP-galactose
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2c20, PDBe:2c20, PDBj:2c20
PDBsum2c20
PubMed
UniProtA0A6L8PTV5

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