Structure of PDB 2bo8 Chain D Binding Site BS02

Receptor Information

>2bo8 Chain D (length=380) Species: 29549 (Rhodothermus marinus)

SLVVFPFKHEHPEVLLHNVRVAAAHPRVHEVLCIGYERDQTYEAVERAAP
EISRATGTPVSVRLQERLGTLRPGKGDGMNTALRYFLEETQWERIHFYDA
DITSFGPDWITKAEEAADFGYGLVRHYFPRASTDAMITWMITRTGFALLW
PHTELSWIEQPLGGELLMRREVAAMLYEDERVRRRSDWGIDTLYTFVTVQ
QGVSIYECYIPEGKAHRLYGGLDDLRTMLVECFAAIQSLQHEVVGQPAIH
RQEHPHRVPVHIAERVGYDVEATLHRLMQHWTPRQVELLELFTTPVREGL
RTCQRRPAFNFMDEMAWAATYHVLLEHFQPGDPDWEELLFKLWTTRVLNY
TMTVALRGYDYAQQYLYRMLGRYRYQAALE

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 2bo8 Chain D Residue 500

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2bo8 Structural dissection and high-throughput screening of mannosylglycerate synthase.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): D102 H217
• Binding residue (residue number reindexed from 1): D101 H216
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.4.1.269: mannosylglycerate synthase.

Gene Ontology

Molecular Function

• GO:0016740 transferase activity
• GO:0016758 hexosyltransferase activity
• GO:0042802 identical protein binding
• GO:0046872 metal ion binding
• GO:0102921 mannosylglycerate synthase activity

Biological Process

• GO:0051479 mannosylglycerate biosynthetic process

External links

• PDB: RCSB:2bo8, PDBe:2bo8, PDBj:2bo8
• PDBsum: 2bo8
• PubMed: 15951819
• UniProt: Q9RFR0|MGS_RHOMR Mannosylglycerate synthase (Gene Name=mgs)