Structure of PDB 2bme Chain D Binding Site BS02

Receptor Information
>2bme Chain D (length=174) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIIN
VGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTN
WLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETS
ALTGENVEEAFVQCARKILNKIES
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2bme Chain D Residue 1180 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2bme High Resolution Crystal Structures of Human Rab4A in its Active and Inactive Conformations.
Resolution1.57 Å
Binding residue
(original residue number in PDB)		S24 T42
Binding residue
(residue number reindexed from 1)		S21 T39
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q69
Catalytic site (residue number reindexed from 1) Q66
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0032482 Rab protein signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:2bme, PDBe:2bme, PDBj:2bme
PDBsum2bme
PubMed15907487
UniProtP20338|RAB4A_HUMAN Ras-related protein Rab-4A (Gene Name=RAB4A)

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