Structure of PDB 1su1 Chain D Binding Site BS02

Receptor Information
>1su1 Chain D (length=182) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRNALPEGY
APAKVVERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRL
FLTHGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPK
GGNPASYGMLDNDVLSVIALNDQSIIAQVAIN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1su1 Chain D Residue 308 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1su1 Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		D37 N73 H105 H127
Binding residue
(residue number reindexed from 1)		D36 N72 H104 H126
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.4.-
Gene Ontology
Molecular Function
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Cellular Component
GO:0005829 cytosol
GO:0032991 protein-containing complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:1su1, PDBe:1su1, PDBj:1su1
PDBsum1su1
PubMed17586769
UniProtP67095|YFCE_ECOLI Phosphodiesterase YfcE (Gene Name=yfcE)

[Back to BioLiP]