Structure of PDB 1rlt Chain D Binding Site BS02

Receptor Information
>1rlt Chain D (length=268) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVASGNQYYQLI
SFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLN
LPDEQIPLVIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKR
WDLSPQNVVAIGDSGNDAEMLKMARYSFAMGNAAENIKQIARYATDDNNH
EGALNVIQAVLDNTYPFN
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain1rlt Chain D Residue 804 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1rlt Ybiv from Escherichia coli K12 is a HAD phosphatase.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D9 M10 D11 S44 K192
Binding residue
(residue number reindexed from 1)		D7 M8 D9 S42 K190
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.23: sugar-phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
GO:0050286 sorbitol-6-phosphatase activity
GO:0050308 sugar-phosphatase activity
GO:0103026 fructose-1-phosphatase activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:1rlt, PDBe:1rlt, PDBj:1rlt
PDBsum1rlt
PubMed15657928
UniProtP75792|SUPH_ECOLI Sugar phosphatase YbiV (Gene Name=ybiV)

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