Structure of PDB 1hxy Chain D Binding Site BS02

Receptor Information
>1hxy Chain D (length=212) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLHDKSELTDLALANAYGQYNHPFIKENIKSDEISGEKDLIFRNQGDSGN
DLRVKFATADLAQKFKNKNVDIYGASFYYKCEKISENISECLYGGTTLNS
EKLAQERVIGANVWVDGIQKETELIRTNKKNVTLQELDIKIRKILSDKYK
IYYKDSEISKGLIEFDMKTPRDYSFDIYDLKGENDYEIDKIYEDNKTLKS
DDISHIDVNLYT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1hxy Chain D Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1hxy Crystal Structure of a Superantigen Bound to MHC Class II Displays Zinc and Peptide Dependence
Resolution2.6 Å
Binding residue
(original residue number in PDB)		H206 D208
Binding residue
(residue number reindexed from 1)		H205 D207
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042289 MHC class II protein binding
GO:0042608 T cell receptor binding
GO:0046872 metal ion binding
GO:0090729 toxin activity
Biological Process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1hxy, PDBe:1hxy, PDBj:1hxy
PDBsum1hxy
PubMed11432818
UniProtP0A0M0|ETXH_STAAU Enterotoxin type H (Gene Name=entH)

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