Structure of PDB 4v5g Chain CZ Binding Site BS02

Receptor Information
>4v5g Chain CZ (length=374) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVHVEYETAKRHYSHVD
CPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYI
VVFMNKVDMVDDPELLDLVEMEVRDLLNQYEFPGDEVPVIRGSALLALEQ
MHRNPKTRRGENEWVDKIWELLDAIDEYIPTPVRDVDKPFLMPVEDVFTI
TGRGTVATGRIERGKVKVGDEVEIVGLAPETRRTVVTGVEMHRKTLQEGI
AGDNVGVLLRGVSREEVERGQVLAKPGSITPHTKFEASVYVLKKEEGGRH
TGFFSGYRPQFYFRTTDVTGVVQLPPGVEMVMPGDNVTFTVELIKPVALE
EGLRFAIREGGRTVGAGVVTKILE
Ligand information
>4v5g Chain CY (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcugauauagcucaguugguagagcgcacccuuggugagggugaggucgg
caguucgaaucugccuaucagcaccaT
.<<<<<<..<<<<........>>>>.<<<<<<.....>>>>>>.....<<
<<.........>>>>>>>>>>......
Receptor-Ligand Complex Structure
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PDB4v5g The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D87 K90 F229 T230 I231 R234 V237 T239 G269 E271 H273 R274 G287 R300 R330 H331 T332 F335 Y338 R339 Q341 D348 T350 I375 K376 E390 G391 G392
Binding residue
(residue number reindexed from 1)		D56 K59 F198 T199 I200 R203 V206 T208 G238 E240 H242 R243 G256 R269 R299 H300 T301 F304 Y307 R308 Q310 D317 T319 I344 K345 E359 G360 G361
Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4v5g, PDBe:4v5g, PDBj:4v5g
PDBsum4v5g
PubMed19833920
UniProtQ5SHN6|EFTU1_THET8 Elongation factor Tu-A (Gene Name=tufA)

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