Structure of PDB 4v63 Chain CX Binding Site BS02

Receptor Information
>4v63 Chain CX (length=354) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLDKLDRLEEEYRELEALLSDPEVLKDKGRYQSLSRRYAEMGEVIGLIRE
YRKVLEDLEQAESLLDDPELKEMAKAEREALLARKEALEKELERHLLPKD
PMDERDAIVEIRAGTGGEEAALFARDLFNMYLRFAEEMGFETEVLDSHPT
DLGGFSKVVFEVRGPGAYGTFKYESGVHRVQRVPVTETQGRIHTSTATVA
VLPKAEEEDFALNMDEIRIDVMRASGPGGQGVNTTDSAVRVVHLPTGIMV
TCQDSRSQIKNREKALMILRSRLLEMKRAEEAERLRKTRLAQIGTGERSE
KIRTYNFPQSRVTDHRIGFTTHDLEGVLSGHLTPILEALKRADQERQLAA
LAEG
Ligand information
Receptor-Ligand Complex Structure
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PDB4v63 Structural basis for translation termination on the 70S ribosome
Resolution3.207 Å
Binding residue
(original residue number in PDB)
G116 G117 E119 P184 T186 R191 I192 H193 T194
Binding residue
(residue number reindexed from 1)
G116 G117 E119 P184 T186 R191 I192 H193 T194
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4v63, PDBe:4v63, PDBj:4v63
PDBsum4v63
PubMed18596689
UniProtQ72HB8|RF1_THET2 Peptide chain release factor 1 (Gene Name=prfA)

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