Structure of PDB 4v7e Chain CV Binding Site BS02

Receptor Information
>4v7e Chain CV (length=140) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSKRGRGGSAGNKFRMSLGLPVAATVNCADNTGAKNLYIISVKGIKGRLN
RLPSACVGDMVMATVKKGKPDLRKKVMPAVIVRQRKPWRRKDGVFMYFED
NAGVIVNPKGEMKGSAITGPIGKECADLWPRIASAANAIV
Ligand information
>4v7e Chain Aa (length=3391) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgcgaccccaggucaggcgggacuaccgcugaguuuaagcauauaaaua
agcggaggagaagaaacuuacaaggauuccccuaguaacggcgagcgaac
cgggagcagcccagcuugagaaucgggcggcugugccguccgaauuguag
ucuggagaggcguccucagcgacggaccgggcccaaguccccuggaaagg
ggcgccugggagggugagagccccguccggcccggacccugucgccccac
gaggcgccgucaacgagucggguuguuugggaaugcagcccaaaucgggc
gguagacuccguccaaggcuaaauacaggcgagagaccgauagcgaacaa
guaccgcgagggaaagaugaaaaggacuuugaaaagagagucaaagagug
cuugaaauugccgggagggaagcggaugggggccggcgaugcgccccggc
cguaugcggaacggcucuugcugguccgccgcucggcucggggcguggac
uguugucggccgcgccggcggccaaagcccgggggcuccgcgcccccggc
agccgucgucggcacggccgguacccgcgcgccgaaaggcgugccccucg
gggcacugcgcugcaacgcccugcgggcuccccauccgacccgucuugaa
acacggaccaaggagucugacaugcgugcgagucgacggguucugaaacc
ugggaugcgcaaggaagcugacgagcgggaggcccucacgggccgcaccg
cuggccgacccugaucuucugugaaggguucgaguuggagcacgccuguc
gggacccgaaagauggugaacuaugccugagcggggcgaagccagaggaa
acucugguggaggcucgaagcgauacugacgugcaaaucguucgucugac
uuggguauaggggcgaaagacuaaucgaaccaucuaguagcugguucccu
ccgaaguuucccucaggauagcuggagcccauuacgaguucuaucaggua
aagccaaugauuagaggcauuggggacgcaacguccucgaccuauucuca
aacuuuaaauagguaggauggcgcggcugcuucggugagccgugccaugg
aaucgggugcuccaagugggccauuuuugguaagcagaacuggcgaugcg
ggaugaaccggaagccggguuacggugcccaacugcgcgcuaaccuagaa
cccacaaaggguguuggucgauuaagacagcaggacgguggucauggaag
ucgaaauccgcuaaggaguguguaacaacucaccugccgaaucaacuagc
cccgaaaauggauggcgcugaagcgcgcgacccacacccggccaucuggg
cgagugccaugccccgaugaguaggagggcgcggcggccgaugcaaaacc
cggggcgcgagcccgggcggagcggccgucggugcagaucuuggugguag
uagcaaauauucaaaugagaacuuugaaggccgaagaggagaaagguucc
augugaacggcacuugcacauggguaagccgauccuaagggaagggguaa
ccccggcagauagcgcgaucacgcgcauccccgaaagggaaucggguuaa
gauuucccgagccgggauguggcgguugacggcgacguuaggaaguccgg
agacgccggcgggggccucgggaagaguuaucuuuucugcuuaacggccu
gccaacccuggaaacgguucagccggagguaggguccaguggccggaaga
gcacacgucgcgcgguguccggugcgcccccggcggcccaugaaaauccg
gaggaccgaguaccguucacgcccggucguacucauaaccgcaucagguc
uccaaggugaacagccucuggccaauggaacaauguaggcaagggaaguc
ggcaaaacggauccguaacuucgggaaaaggauuggcucugaggacuggg
cucgggggucccggccccgaacccgucggcugucggcggauugcucgagc
ugcucacgcggcgagagcgggucgccgcgugccggccgggggacggaccg
ggaaucgccccuucgggggcuuuccccgagcaugaaacagucgacucaga
acugguacggacaaggggaauccgacuguuuaauuaaaacaaagcauugc
gaugguccucgcggaugcugacgcaaugugugauuucugcccagugcucu
gaaugucaaagugaagaaauucaaccaagcgcggguaaacggcgggagua
acuaugacucucuuaagguagccaaaugccucgucaucuaauuagugacg
cgcaugaaugaauggauuaacgagauucccacugucccugucuacuaucc
agcgaaaccacagccaagggaacgggcuuggcggaaucagcggggaaaga
agacccuguugagcuugacucuaguccgacuuugugaaaugacuugagag
guguaggauaagugggagcccucacgggcgcaagugaaauaccacuacuu
uuaacguuauuuuacuuauuccgugggucggaagcggggcaugccccucc
uuuuggcuccaaggcccggucuuaccgggccgauccgggcggaagacauu
gucagguggggaguuuggcuggggcggccaaucuguuaaaagauaacgca
gguguccuaagaugagcucaacgagaacagaaaucucguguggaacaaaa
ggguaaaagcucguuugauucugauuuccaguacgaauacgaaccgugaa
agcguggccuaucgauccuuuagacuucggaguuugaagcuagagguguc
agaaaaguuaccacagggauuacuggcuuguggcagccaagcguucauag
cgacguugcuuuuugauccuucgaugucggcucuuccuaucauugcgaag
cagaauucaccaaguguuggauuguucacccaccaauagggaacgugagc
uggguuuagaccgucgugagacagguuaguuuuacccuacugaugacagu
gucgcgauaguaauucaaccuaguacgagaggaaccguugauucacacaa
uuggucaucgcgcuugguugaaaagccaguggcgcgaagcuaccgugugc
cggauuaugacugaacgccucuaagucagaauccaagcuagcaugcgacg
ccugcgcccgccgcccgccccgacccacguuaggggcgcuugcgccccca
agggcccgugccauuggcuaagccgguccggccgaagugccgcggucggc
cgccucgaagcucccuucccaacgggcggugggcugaauccuuugcagac
gacuuaaauacgcgacggggcauuguaaguggcagaguggccuugcugcc
acgauccacugagauccaguccccgcgucgcacggauucgu
..........................<<<<<.....<......>......
>>>>>...........<<....>>..<<<<<.......<.....>.....
.>>>>>..<<<...........<<<<<<<<<...>>>>>>>>>.......
......<<<<<<.<<<<.<<<<<<<.<<<<<<<.....<<<<......>>
>>.((......<<<.....))>>>....>>>>>>>...>>>>>>>.....
>>>>>>>>.>>........<<<<<<<........>>>>>>>.....<<<<
<..((((((>>>>>..>>>...............................
...<<....>>...............<<<<....>>>>............
........................<<<<<<<<<<.<<...<<<<<<<<<<
<<..<<<<<<.<<<<....>>>>.>>>>.>>..>>>>.>>>>>>>>....
<<<<<<<<<<<<.<<<<<<<<.......<<<<<<<<.....>>>>>>>>.
.....>>>>>>>>.>>>>>>>.....<<<<<<<....>>><<<<<<....
>>>>>>.>>>>..>>>>>....>>.>>>.>>>>>>>....<<<<......
..>>>><<<<<<.....<<<<<.<<<<<<..<<<...<<.<.....>.>>
...>>>...<......>......<<<<<..<<<<<....>>>>>...>>>
>><<<<<<<<<....<....>....>>>.>>>.>>>...>>>>>>.>>>>
>...<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<<...
.>>>>>>>.....>>>...<<<<.<<.<<........>>>>>>>>....>
>>>>>>>>...<<.......>>......>>>>>>...>..>.>>..<<<<
<<....<.<<<....>>>.><<<<<<<<.<....<<<.<<<<<<<.....
<<<....<<<....<<<....<<<<<<.....>>>>>>..>>>....>>>
..>>.>.....>>>>>...<<<<<<<<<.........>>>>>>>>>....
>>>>>.>.>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<
<......>>>...<<<<<<<...<<<(((.....<<<<<<......<<..
........<<<.<<<<<<.<<<.......<<<<<.<<.....<.......
..>.....>>.........<<......>>...>>>>>...>>>.>>>>>>
>>>..........))).>>...>>>>>>.>>>...>>>>>>><<<<.<<<
<.........>>>>.>>>>....>>>>>><<<<<<<<<<<........<<
<.<<<<....>>>>>>>.....>>>>>>>>>.>>.....>>>>>><<...
..<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<...<<
<<<<...<<.....>>.>>>>>>....((<<<<<<...<<<...<<<...
.>>>........<<<<<....>>>>>...>>>....>>...<<<<<....
....>>>.>>))<<<<.<<<<..<....<<<....>>>.......<<<<<
<...<<<<.<<<<<<<.<<<<<.<<<<...[[..>>>>.><...<<<<<.
....<<<<<<.....<<.....>>.....>>>>>>.....>>>>>....>
<<<<..........>>>>>>>>...>>>>>>>.>>>>.........>>>>
>>..........>....>>>>>>>>>>>>..>>.....<<......>>>>
>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<......
.........<<<<<....<....>.....>>>>><<.<<<<<<<<<<<.<
<<<<<<<.<<<<<<..<<<..<<<<<<<<<<<.<<<<<<.<<<<<<..<<
<<<....>>>>>..>>>>>>.>>>>>>>>.>>>>>>..>>>..>>>.>>>
>>>...<<<<......>>>>...>>>>>>>>......>>>>>..>>>>>>
.>>............<<<<<<<<<..<<<.........>>>..<<<..<<
....<<<<....>>>>......>>....>>>...<<<.<<<..<<<<<<.
<...<<.....<<<<....>>>>.....>>.>>>>>..>>>>><<<<<<.
......>>>>>>........<...........<<<<<.......>>>>>.
....>....>>>........>>.>>>>>>>.....>>.>>>>>>>..>>>
>>>....>>....<<<<<........>>>>>....<<<<<..<<<.<<..
....<<<<.<<<<<<..<<<<<.<<<.<<<...<<<<<<<<<<<<<<<<<
...........<<<<..<<<<....>>>>............>>>>..>>>
>>>>.>>>>>>>>>>...<<<<<.....<<<<...<<<..........>>
>................<<<<<....>>>>>..>>>>..>>>>>......
>>>.>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>
>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<...(
((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>.<<<...
.>>>.>>)))......<<<<<<<.<<<<.))))))>>>>>>>>>>>....
.....>>>>..>>>>>>.......<<.<.<.<<<<<<...<<.......>
>...>>>>>>...>>.>.>.......<<<<<.<<<<<<..<<<.<.<<<.
.....>>>.>...>>>.<<<.<.....>.>>>.....>>>>>..>...>>
>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>>>....<<
<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<..
.<<<<....<<<<<<<<<.]]...>>>>..>>>>>...>>>>..>>>>>.
.<<<...<<<<<...........>>>>>...>>>..>>>>....>>>>>>
>....<<<<<<<<<<<<......<<<......<<<<..<....>.>>>>.
.>>>...........<<<...<<<<<<.<<<<......>>>>.>.>>>>>
.>>>..................>>>>>>>>>>>>.<<<<<.<........
.....>.........<<<<<.<<<....<<<<....<<<<<......>>>
>>...>>>>...>>>....>>>>.>.........>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v7e Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Resolution5.5 Å
Binding residue
(original residue number in PDB)
M1 S2 K3 R4 A10 K13 F14 R15 S17 G19 Y38 I40 S41 V42 K43 G44 I45 K46 R48 L49 N50 R51 L52 P53 M62 T64 K74 R85 K86 R89
Binding residue
(residue number reindexed from 1)
M1 S2 K3 R4 A10 K13 F14 R15 S17 G19 Y38 I40 S41 V42 K43 G44 I45 K46 R48 L49 N50 R51 L52 P53 M62 T64 K74 R85 K86 R89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v7e, PDBe:4v7e, PDBj:4v7e
PDBsum4v7e
PubMed24499919
UniProtQ5I7K4

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