Structure of PDB 6xu7 Chain CS Binding Site BS02

Receptor Information
>6xu7 Chain CS (length=173) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLLKEYEVVGRKLPSEKEPQTPLYKMRIFAPDNIVAKSRFWYFLRQLKKF
KKTTGEIVSIKQVYETSPVKIKNFGIWLRYDSRSGTHNMYREYRDLTVGG
AVTQCYRDMGARHRARAHSIQIIKVDSIPAAKTRRVHVKQFHDSKIKFPL
VQRVHHKGNRKLFSFRKPRTYFQ
Ligand information
>6xu7 Chain A5 (length=3707) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuauauacaaccucaacucauaugggacuacccccugaauuuaagcauau
uaauuaggggaggaaaagaaacuaacaaggauuuucuuaguagcggcgag
cgaaaagaaaacaguucagcacuaagucacuuugucuauauggcaaaugu
gagaugcaguguauggagcgucaauauucuaguaugagaaauuaacgauu
uaaguccuucuuaaaugaggccauuuacccauagagggugccaggcccgu
auaacguuaaugauuacuagaugauguuuccaaagagucguguugcuuga
uagugcagcacuaagugggugguaaacuccaucuaaaacuaaauauaacc
augagaccgauaguaaacaaguaccgugagggaaaguugaaaagaacucu
gaauagagaguuaaacaguacgugaaacugcuuagagguuaagcccgaug
aaccugaauauccguuauggaaaauucaucauuaaaauuguaauauuuaa
auaauauuaugagaauagugugcauuuuuuccauauaaggacauuguaau
cuauuagcauauaccaaauuuaucauaaaauauaacuuauaguuuauucc
aauuaaauugcuugcauuuuaacacagaauaaauguuauuaauuugauaa
agugcugauagauuuauaugauuacagugcguuaauuuuucggaauuaua
uaauggcauaauuaucauugauuuuuguguuuauuauaugcacuuguaug
auuaacaaugcgaaagauucaggauaccuucgggacccgucuugaaacac
ggaccaaggagucuaacauaugugcaaguuauugggauauaaaccuaaua
gcguaauuaacuugacuaauaaugggauuaguuuuuuagcuauuuauagc
uaauuaacacaaucccggggcguucuauauaguuauguauaauguauauu
uauauuauuuaugccucuaacuggaacguaccuugagcauauaugcugug
acccgaaagauggugaacuauacuugaucagguugaagucaggggaaacc
cugauggaagaccgaaacaguucugacgugcaaaucgauugucagaauug
aguauaggggcgaaagaccaaucgaaccaucuaguagcugguuccuuccg
aaguuucccucaggauagcuggugcauuuuaauauuauauaaaauaaucu
uaucugguaaagcgaaugauuagaggccuuagggucgaaacgaucuuaac
cuauucucaaacuuuaaauggguaagaaccuuaacuuucuugauaugaag
aucaagguuaugauauaaaugucccagugggccacuuuugguaagcagaa
cuggcgcugugggaugaaccaaacguaauguuacgugcccaaauuaacaa
cucaugcagauaccaugaaaggcguugguugcuuaaaacagcaggacggu
gaucauggaagucgaaauccgcuaaggaguguguaacaacucaccugccg
aagcaacuagcccuuaaaauggauggcgcuuaaguuguauaccuauacau
uaccgcuaaaguagaugauuuauauuacuugugauauaaauuuugaaacu
uuagugaguaggaagguacaaugguaugcguagaaguguuuggcguaagc
cugcauggagcugccauugguacagaucuugguggauaguagcaaauaau
cgaaugagagccuuggaggacugaaguggagaaggguuucgugugaacag
ugguugaucacgaguuagucgguccuaaguucaaggcgaaagcgaaaauu
uucaaguaaaacauaauuuugaacgaaagggaauacgguuccaauuccgu
aaccuguugaguauccguuuguuauuaaauaugggccucgugcucauccu
ggcaacaggaacgaccauaaagaagccgucgagagauaucggaagaguuu
ucuuuucuguuuuauagccguacuaccauggaagucuuucgcagagagau
augguagaugggcuagaagagcaugacauauacuguugugucgauauuuu
cuccucggaccuugaaaauuuaugguggggacacgcaaacuucucaacag
gccguaccaauauccgcagcuggucuccaaggugaagagucucuagucga
uagaauaauguagguaagggaagucggcaaauuagauccguaacuucggg
auaaggauuggcucugaagauugagauagucggccuugauugggaaacug
gaacuuucuugcuaaauuauaacgauuaucaauuaacaaucaauucagaa
cuggcacggacuuggggaauccgacugucuaauuaaaacaaagcauugug
auggcccuagcggguguugacacaaugugauuucugcccagugcucugaa
ugucaaagugaagaaauucaaguaagcgcgggucaacggcgggaguaacu
augacucucuuaagguagccaaaugccucgucaucuaauuagugacgcgc
augaauggauuaacgagauuccuacugucccuaucuacuaucuagcgaaa
ccacagccaagggaacgggcuuggaauaauuagcggggaaagaagacccu
uuugagcuugacucuaaucuggcaguguaaggagacauaagagguguaga
auaagugggagauauuagaccucgguuugguaucgucaaugaaauaccac
uacucuuauuguuuccuuacuuacuugauuaaauggaacguguaucauuu
ccuagauuggguuuugaugcaagcuucuugaucaaaguaucacgaguuug
uuauauaaucgcaaacaaauuugguauaacuccaauuacucagguaugau
ccaauucaaggacauugccagguagggaguuugacuggggcgguacaucu
cucaaauaauaacggaggugucccaaggccagcucagugcggacagaaac
cacacauagagcaaaagggcaaaugcugacuugaucucgguguucaguac
acacagggacagcaaaagcucggccuaucgauccuuuugguuuaaagagu
uuuuaacaagaggugucagaaaaguuaccauagggauaacuggcuugugg
cggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggcuc
uuccuaucauugugaagcaaaauucaccaagcguuggauuguucacccau
gcaagggaacgugagcuggguuuagaccgucgugagacagguuaguuuua
cccuacuaaugacaaaacguuguugcgacagcauuccugcguaguacgag
aggaacccgcagguacggaccaauggcacaauacuuguucgagcgaacag
ugguaugacgcuacguccguuggauuaugccugaacgccucuaaggucgu
auccgugcuggacugcaaugauaaauaaggggcaauuugcauuguauggc
uucuaaaccauuuaaaguuuauaauuuacuuuauaaacgacaauggaugu
gaugccaauguaauuuguaacauaguaaauugggaggaucuucgaucacc
ugaugccgcgcuaguuacauauaaaagcauuauuuaauacaaugacaaag
ccuagaaucaauuguaaacgacuuuuguaacaggcaagguguuguaagug
guugagcagcugccauacugcgauccacugaagcuuauccuuugcuugau
gauucga
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Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xu7 Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Resolution4.9 Å
Binding residue
(original residue number in PDB)
K65 Y68 T70 P72 V73 S86 R87 M93 Y94 R95 R111 A115 R116 R118 R139 K149 V155 Q156 R157 H159 H160 G162 N163 R164 F169 R170 P172 R173 T174 Y175 F176 Q177
Binding residue
(residue number reindexed from 1)
K61 Y64 T66 P68 V69 S82 R83 M89 Y90 R91 R107 A111 R112 R114 R135 K145 V151 Q152 R153 H155 H156 G158 N159 R160 F165 R166 P168 R169 T170 Y171 F172 Q173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6xu7, PDBe:6xu7, PDBj:6xu7
PDBsum6xu7
PubMed34283226
UniProtP41093|RL18A_DROME Large ribosomal subunit protein eL20 (Gene Name=RpL18A)

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