Structure of PDB 8pv7 Chain CM Binding Site BS02

Receptor Information
>8pv7 Chain CM (length=217) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LVPETLLKKRKSQEKARAERAAAVIFKRAEKYVKEYREQEREKIRLARIA
KQQGAKLVFVIRIKGINKIPPKPRKILQLLRLRQINNGVFVKVTKATAEM
IKIVEPWVAYGYPNLKSVRELIYKRGYGKVNGQRIPLTDNAIIEENLGKY
GIICIEDLIHEIFTVGPNFKQAANFLWPFKLSNPNGGFRPRKFKHFIEGG
DLGNREEHINALIRAMN
Ligand information
>8pv7 Chain C3 (length=82) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uucaaccaucaagcccugggcuuguguuggggacccgcggcugcucgcgg
gcccugaaaagcaguggcgggcgugccagccg
.........<<<<<<...>>>>>>....<<<<.<<<<<<<....>>>>>>
>>>>>.........<<<<<<<..>.>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8pv7 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.12 Å
Binding residue
(original residue number in PDB)		I50 F51 R53 E55 R73
Binding residue
(residue number reindexed from 1)		I25 F26 R28 E30 R48
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pv7, PDBe:8pv7, PDBj:8pv7
PDBsum8pv7
PubMed37921038
UniProtG0SFL0

[Back to BioLiP]