Structure of PDB 6rxv Chain CM Binding Site BS02

Receptor Information
>6rxv Chain CM (length=445) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIKALTRSITAQQAPGSDVQRAPRNLAPELHPFERAREYQRALNAVKLER
MFAKPFLGQLGNGHVQGVYSMCKDKNSLNCIASGSGDGVVKVWDLTTRDE
ETWRVAAHNNIVKGLTFTNDKKLLSCATDGIKLWDPYASPSNTTPIATWQ
EGGPYTSLSFHRSANTFAASSGQGCIRIWDLEHSTAGQAIQWPSFVDTIT
DVCFNQVETSVIGSVATDRSIILFDLRTNMPVIKTVLHFACNRIVFNPME
AMNLAVASEDHNIYIFDARNFDKALNIQKGHVAAVMDVEFSPTGEELVSG
SYDRTIRLWRRDAGHSRDVYHTKRMQRVFRTMWTMDSKYILTGSDDGNVR
LWRANASERSGVKATRQRQALEYNNALLDRYGHLPEIRRIRRHRHLPKVV
KKATEIKREELAAIKRREENERKHSNKKYEKRKSEREKAVLVKQQ
Ligand information
>6rxv Chain C2 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgacaauacuucagagaaucauuucuauaguaguuguccucucuugug
uuuccuaaaggagccacagaucccacccggguugaugaacgagauccucg
gcgccagugagguccauuuacucucgcucuaccugcaaagguggcggucg
cgugccucgucucgcggcuguauagagaguggcgaugaucuguaccccgc
ggggugggugucgauggaagucugaccggc
..................................................
..........................<<<<......<.......<<<<<<
<<<<.<<............<<<<<<...<<<<<<....>>>>>><<<<<<
<<.<......>.>>>>>>>>....>>>>>>.........>>.<<<<<<..
>>>>>>.>>>>>>>.>>>...>...>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxv Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		D19 K48 L49 M52 F53 A54 K55 P56 F57 Q60 V320 Y321 H322 K324 R325 R351 S358 R360 R367 Q368 H394 H396
Binding residue
(residue number reindexed from 1)		D18 K47 L48 M51 F52 A53 K54 P55 F56 Q59 V319 Y320 H321 K323 R324 R350 S357 R359 R366 Q367 H393 H395
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6rxv, PDBe:6rxv, PDBj:6rxv
PDBsum6rxv
PubMed31378463
UniProtG0RY94

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