Structure of PDB 8pv4 Chain CJ Binding Site BS02

Receptor Information
>8pv4 Chain CJ (length=382) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKAKKKGKSGAARNYMTRTQAVKKLQLSLPDFRKLCIWKGIYPREPRDRR
KVNKSATASTTFYYTKDIQYLLHEPLLQKFREQKALEKKISRALGRGDVS
NAARLERNANLPEKTGKPRYTLNHIIRERYPTFQDALRDLDDCLSMLFLF
ANLPSTTAVPAKMIARCERLCHEFQHYLIVTHSLRKSFLSIKGIYYQANI
QGEDILWLVPYKFNQRIVGDVDFRIMGTFVEFYMTLLGFVNYRLYTSIGL
KYPPKFDQVKDDQGAELAAFSLEGLNDPSQLFANFTFFLSRETPRQPLEF
ILRAFGCKRIGWDAVLGEGAFTTDESDPRITHQIIDRPGRYPGRIYVQPQ
WVWDSINDEELKPPELYAPGAQLPPHLSPFVK
Ligand information
>8pv4 Chain C2 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuuucaacaacggaucucuugguucuggcaucgaugaagaacgcagc
gaaaugcgauaaguaaugugaauugcagaauuccgugaaucaucgaaucu
uugaacgcacauugcgcccgccgguauuccggcgggcaugccuguucgag
cgucau
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>..............>>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pv4 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K3 S10 G11 R14 N15 K25 Y65 Q70 H74 K89 K90
Binding residue
(residue number reindexed from 1)		K2 S9 G10 R13 N14 K24 Y64 Q69 H73 K88 K89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pv4, PDBe:8pv4, PDBj:8pv4
PDBsum8pv4
PubMed37921038
UniProtG0SHX6

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