Structure of PDB 7aju Chain CH Binding Site BS02

Receptor Information
>7aju Chain CH (length=467) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENPADKRRRLAKQYLENLKSEANDILTDIIASRLKEDVAEQQGRVFRYFG
DKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFA
YTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYD
EILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLA
FRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCV
TVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKEPLFFCEGSIDVV
SMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGET
DEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNL
RSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIAN
VSGARNGIYSAVIDQTG
Ligand information
>7aju Chain D4 (length=223) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucaaggaucaucuauaggaaucgucacucuuugacucuu
cccacugaauccaacuugguugaugagucccauaaccuuuguaccccaga
gugagaaauagcuugguccgcaauccuuagcgguucggccaucuauaauu
uugaauaaaaauuuugccguugcuauggcgcgaugaucacccaugggugg
guacaaauggcagucugacaagu
..................................................
.............<<<<<.................<<<<<<<<<<<....
<........<<..<<<.<<<.<<<<......>>>>>>>>>>.>>..<<<<
<<....>>>.>>>..<<<<<....>>>>>........><<<<..>>>>>>
>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7aju Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R151 G153 D179 K180 R207 Y213 A218 S264 E266 S267 K545 R551 G558 R560
Binding residue
(residue number reindexed from 1)		R64 G66 D92 K93 R120 Y126 A131 S177 E179 S180 K440 R446 G453 R455
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aju, PDBe:7aju, PDBj:7aju
PDBsum7aju
PubMed33326748
UniProtQ06506|RRP9_YEAST Ribosomal RNA-processing protein 9 (Gene Name=RRP9)

[Back to BioLiP]