Structure of PDB 8oeq Chain CE Binding Site BS02
Receptor Information
>8oeq Chain CE (length=86) Species:
5476
(Candida albicans) [
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GKGTPSLGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKMRSHNWAL
KAKRRRTTGTGRMAYLKHVTRRFKNGFQTGVAKAQT
Ligand information
>8oeq Chain AU (length=158) [
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aaacuuucaacaacggaucucuugguucucgcaucgaugaagaacgcagc
gaaaugcgauacguaauaugaauugcagauauucgugaaucaucgaaucu
uugaacgcacauugcgcccucugguauuccggagggcaugccuguuugag
cgucguuu
.........................................<<<<<<.((
.....>>>.....<.<<<<.....))............>>.>>..>...>
>>....<<.....>><<<<<<<<<....>>>>>>>>>.............
........
Receptor-Ligand Complex Structure
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PDB
8oeq
Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution
3.3 Å
Binding residue
(original residue number in PDB)
R21 G23 V29 Y39 A42 T59 G60 T61 G62 R63 M64 Y66 L67 K68 R72 F74 K75 N76 Q79 G81 V82 A83 A85 Q86
Binding residue
(residue number reindexed from 1)
R20 G22 V28 Y38 A41 T58 G59 T60 G61 R62 M63 Y65 L66 K67 R71 F73 K74 N75 Q78 G80 V81 A82 A84 Q85
External links
PDB
RCSB:8oeq
,
PDBe:8oeq
,
PDBj:8oeq
PDBsum
8oeq
PubMed
UniProt
A0A1D8PF45
|RL37B_CANAL Large ribosomal subunit protein eL37 (Gene Name=RPL37B)
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