Structure of PDB 6rxt Chain CE Binding Site BS02

Receptor Information
>6rxt Chain CE (length=121) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAAWPKAEDPALVQELLDCVQQASHYRQLKKGANETTKSVNRGTSELVIL
AADTQPLSIVLHIPLICEEKNVPYVYVPSKVALGRACGVSRAVIAVSLTS
NEASDLNSKIRALRDKVERLA
Ligand information
>6rxt Chain C2 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcgacaauacuucagagaaucauuucuauaguaguuguccucucuugug
uuuccuaaaggagccacagaucccacccggguugaugaacgagauccucg
gcgccagugagguccauuuacucucgcucuaccugcaaagguggcggucg
cgugccucgucucgcggcuguauagagaguggcgaugaucuguaccccgc
ggggugggugucgauggaagucugaccggc
..................................................
..........................<<<<......<.......<<<<<<
<<<<.<<............<<<<<<...<<<<<<....>>>>>><<<<<<
<<.<......>.>>>>>>>>....>>>>>>.........>>.<<<<<<..
>>>>>>.>>>>>>>.>>>...>...>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rxt Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
Resolution7.0 Å
Binding residue
(original residue number in PDB)		G37 A38 N39 E40 K43 I64 V94 R96 V98 I99
Binding residue
(residue number reindexed from 1)		G32 A33 N34 E35 K38 I59 V89 R91 V93 I94
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0000470 maturation of LSU-rRNA
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005730 nucleolus
GO:0022625 cytosolic large ribosomal subunit
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071011 precatalytic spliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rxt, PDBe:6rxt, PDBj:6rxt
PDBsum6rxt
PubMed31378463
UniProtG0SGM0

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