Structure of PDB 7zrs Chain CC Binding Site BS02

Receptor Information
>7zrs Chain CC (length=114) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGSSKNCNCQGTRHPVFDIAPNCLHCGKVVCVIEGLNKGKCGHCHEQLIS
DKAEENPELLAAQERLDRLLYFQDTSAERTKIIDNASDFDMNQEVGLWGS
ARERALALKKQQRN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7zrs Chain CC Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zrs Structural basis for clearing of ribosome collisions by the RQT complex.
Resolution4.8 Å
Binding residue
(original residue number in PDB)		C178 H183 C200
Binding residue
(residue number reindexed from 1)		C9 H14 C31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0070530 K63-linked polyubiquitin modification-dependent protein binding
Biological Process
GO:0032790 ribosome disassembly
GO:0045893 positive regulation of DNA-templated transcription
GO:0072344 rescue of stalled ribosome
GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0022626 cytosolic ribosome
GO:0180022 RQC-trigger complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zrs, PDBe:7zrs, PDBj:7zrs
PDBsum7zrs
PubMed36801861
UniProtP36119|RQT4_YEAST RQC trigger complex subunit RQT4 (Gene Name=RQT4)

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