Structure of PDB 9xim Chain C Binding Site BS02
Receptor Information
>9xim Chain C (length=391) Species:
1866
(Actinoplanes missouriensis) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
QATREDKFSFGLWTVGWQARDAFGDATRTALDPVEAVHKLAEIGAYGITF
HDDDLVPFGSDAQTRDGIIAGFKKALDETGLIVPMVTTNLFTHPVFKDGG
FTSNDRSVRRYAIRKVLRQMDLGAELGAKTLVLWGGREGAEYDSAKDVSA
ALDRYREALNLLAQYSEDRGYGLRFAIEPKPNQPRGDILLPTAGHAIAFV
QELERPELFGINPETGHEQMSNLNFTQGIAQALWHKKLFHIDLNGQHGPK
FDQDLVFGHGDLLNAFSLVDLLENGPDGAPAYDGPRHFDYKPSRTEDYDG
VWESAKANIRMYLLLKERAKAFRADPEVQEALAASKVAELKTPTLNPGEG
YAELLADRSAFEDYDADAVGAKGFGFVKLNQLAIEHLLGAR
Ligand information
Ligand ID
MN
InChI
InChI=1S/Mn/q+2
InChIKey
WAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341
[Mn++]
Formula
Mn
Name
MANGANESE (II) ION
ChEMBL
DrugBank
DB06757
ZINC
PDB chain
9xim Chain C Residue 395 [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
9xim
Protein engineering of xylose (glucose) isomerase from Actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
E181 E217 D245 D292
Binding residue
(residue number reindexed from 1)
E178 E214 D242 D289
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
H54 D57 M88 E181 K183 E217 H220 D245 D255 D257 D292
Catalytic site (residue number reindexed from 1)
H51 D54 M85 E178 K180 E214 H217 D242 D252 D254 D289
Enzyme Commision number
5.3.1.5
: xylose isomerase.
Gene Ontology
Molecular Function
GO:0000287
magnesium ion binding
GO:0009045
xylose isomerase activity
GO:0016853
isomerase activity
GO:0046872
metal ion binding
Biological Process
GO:0005975
carbohydrate metabolic process
GO:0042732
D-xylose metabolic process
Cellular Component
GO:0005737
cytoplasm
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:9xim
,
PDBe:9xim
,
PDBj:9xim
PDBsum
9xim
PubMed
1610791
UniProt
P12851
|XYLA_ACTM4 Xylose isomerase (Gene Name=xylA)
[
Back to BioLiP
]