Structure of PDB 8z97 Chain C Binding Site BS02

Receptor Information
>8z97 Chain C (length=552) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESECTLRALVEEYNGACKEAPKEMSKQFTDYNTFKRYTTSKKDHAPQMRL
VYSVRKPWPISMTPSKEIPLVFNGTKLKDTILDLGESKRTRANIVVPDYW
SKYGSQTSLEVVNAILYAEDLKVQRFFSTEWGEIRYGRMLPFRKPVQACP
TIEEVNPASIPHTLLQVFCPQYTTLDSKRKAHMGAVEKLKRVMEPICKVQ
TQESAVHIARSLIDSNKKWLPTVVDHTPRTAEMAHFLCSKYHYVHTNTQD
IDNLCGELVKRSLKCRCPKETLVANLDKITIQGRPMREVLADHDGELPYL
GICRVAMGLSTHHTMKIRSTKFSILNSDHPRIERRFKGKAKVYFQNDQIQ
GYFSCTDRQIDEIKISAPKNAPLLEPLLDICYYGSFIEAFLIHMGLDKDL
SLPLSPELNWKEPALSKVCRVTELDSTVQPYTSATREFVLGETLNVYTQH
ENGLELLICPTEIRSTRGPLPPGTNLSGSEFIDIYQPEGYVQTGVFEEQP
RCYLVDTPDHGLSMGLSRFCVHSQGRYFQYEKKISIWEETDNIKATIDSQ
RD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8z97 Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Resolution2.65 Å
Binding residue
(original residue number in PDB)		R43 T45 K49 D50 A52 P53
Binding residue
(residue number reindexed from 1)		R36 T38 K42 D43 A45 P46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006370 7-methylguanosine mRNA capping
GO:0075526 cap snatching
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8z97, PDBe:8z97, PDBj:8z97
PDBsum8z97
PubMed38816392
UniProtQ9YNA4|PB2_THOGV Polymerase basic protein 2 (Gene Name=Segment)

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