Structure of PDB 8yv8 Chain C Binding Site BS02

Receptor Information
>8yv8 Chain C (length=110) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLP
NIQAVLLPKK
Ligand information
>8yv8 Chain J (length=132) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tctgacacgtgcctggagactagggagtaatccccttggcggttaaaacg
cgggggacagcgcgtacgtgcgtttaagcggtgctagagctgtctacgac
caattgagcggcctcgcgaccgggattctgat
Receptor-Ligand Complex Structure
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PDB8yv8 CDCA7 is a hemimethylated DNA adaptor for the nucleosome remodeler HELLS
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R11 R29 R42 V43 T76 R77
Binding residue
(residue number reindexed from 1)		R2 R20 R33 V34 T67 R68
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006325 chromatin organization
GO:0008285 negative regulation of cell population proliferation
GO:0031507 heterochromatin formation
GO:0061644 protein localization to CENP-A containing chromatin
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0043505 CENP-A containing nucleosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8yv8, PDBe:8yv8, PDBj:8yv8
PDBsum8yv8
PubMed
UniProtP04908|H2A1B_HUMAN Histone H2A type 1-B/E (Gene Name=H2AC4)

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