Structure of PDB 8w8g Chain C Binding Site BS02

Receptor Information
>8w8g Chain C (length=208) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDAGLVAEAEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRNSAEAIIHG
LSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITPLESALMIWGSI
EKEHDKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFERIFGDPNSHMPFK
SKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAA
KVVESKRT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w8g PinX1 suppress tumorigenesis through inhibiting telomerase activity
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R102 N103 E106 I109 H110 L120 I123 Q127 T130 R131 L138 D139 A140 Q141 F142 E146 R147 E192
Binding residue
(residue number reindexed from 1)
R41 N42 E45 I48 H49 L59 I62 Q66 T69 R70 L77 D78 A79 Q80 F81 E85 R86 E131
External links
PDB RCSB:8w8g, PDBe:8w8g, PDBj:8w8g
PDBsum8w8g
PubMed
UniProtP54274|TERF1_HUMAN Telomeric repeat-binding factor 1 (Gene Name=TERF1)

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