Structure of PDB 8w5z Chain C Binding Site BS02

Receptor Information
>8w5z Chain C (length=333) Species: 6944 (Ixodes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFTYVSPDRYVLGPDSRRYPYNNDMPLIFIGGMPRSGTTLVRVLLDAHPD
VRCGEETRVIPRLLSLKQQWVKNPTEMHRLLEGGITDEVLDAAMSAFILE
VIVRHGKPAPRLCNKDPFTLRAAVYLHRLFPRAKFLLMIRDGRAVVHSII
TRKVTITGYDLSDYRQCLKRWNAAMTSMYAQCQQLGPGLCLPVYYEQLVL
HPRAWMQRILAFLEVPWNDSVLHHEQLINQSGIALSKLERSTDQVIKPIN
LGALSKWVGHIPEDVVRDMAKVAPMLAQLGYDPAANPPDYGQPDNFVLNN
TLEIKKKMEEWQARERELEEHRELIKQSIAKKK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8w5z Crystal structure of tick tyrosylprotein sulfotransferase reveals the activation mechanism of the tick anticoagulant protein madanin.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		P73 E95 R97 R101 P156 F157 R160 V193 T194 I195 T196 Y198
Binding residue
(residue number reindexed from 1)		P34 E56 R58 R62 P117 F118 R121 V154 T155 I156 T157 Y159
Enzymatic activity
Enzyme Commision number 2.8.2.20: protein-tyrosine sulfotransferase.
Gene Ontology
Molecular Function
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation

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Molecular Function
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Biological Process
External links
PDB RCSB:8w5z, PDBe:8w5z, PDBj:8w5z
PDBsum8w5z
PubMed38354785
UniProtB7Q097

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