Structure of PDB 8uzx Chain C Binding Site BS02

Receptor Information
>8uzx Chain C (length=160) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQN
PTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLF
RMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYD
EFLEFMKGVE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8uzx Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8uzx Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy.
Resolution5.4 Å
Binding residue
(original residue number in PDB)		D141 N143 D145 E152
Binding residue
(residue number reindexed from 1)		D140 N142 D144 E151
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0031013 troponin I binding
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0060048 cardiac muscle contraction
Cellular Component
GO:1990584 cardiac Troponin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uzx, PDBe:8uzx, PDBj:8uzx
PDBsum8uzx
PubMed38387550
UniProtP63317|TNNC1_PIG Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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