Structure of PDB 8ufj Chain C Binding Site BS02

Receptor Information

>8ufj Chain C (length=443) Species: 192952 (Methanosarcina mazei Go1)

KKCTTKEDVLEAVKERDVKFIRTQFTDTLGIIKSWAIPAEQLEEAFENGV
MFDGSSIQGFTRIEESDMKLALDPSTFRILPWRPATGAVARILGDVYLPD
GNPFKGDPRYVLKTAIKEAEKMGFSMNVGPELEFFLFKLDANGNPTTELT
DQGGYFDFAPLDLGQDVRRDIDYALEHMGFQIEASHHEVAPSQHEIDFRF
GDVLCTADNVVTFKYVVKSIAYHKGYYASFMPKPLFGVNGSGMHSNQSLF
KDGKNVFYDPDTPTKLSQDAMYYIGGLLKHIREFTAVTNPVVNSYKRLVP
GYEAPVYISWSAQNRSSLIRIPATRGNGTRIELRCPDPACNPYLAFALML
RAGLEGIKNKIDPGEPTNVNIFHLSDKEREERGIRSLPADLKEAIDEMKG
SKFVKEALGEHVFSHYLCAKEMEWDEYKAVVHPWELSRYLSML

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8ufj Chain C Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8ufj M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
• Resolution: 2.45 Å
• Binding residue (original residue number in PDB): E137 E192 E199
• Binding residue (residue number reindexed from 1): E133 E188 E195
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 6.3.1.2: glutamine synthetase.

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0004356 glutamine synthetase activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006542 glutamine biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8ufj, PDBe:8ufj, PDBj:8ufj
• PDBsum: 8ufj
• PubMed: 37968329
• UniProt: Q8PY99|GLNA1_METMA Glutamine synthetase (Gene Name=glnA1)