Structure of PDB 8th5 Chain C Binding Site BS02
Receptor Information
>8th5 Chain C (length=125) Species:
9606
(Homo sapiens) [
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KPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHADAVYGQKEIHR
KVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFV
LAPEGSVANKFYVHNDIFRYQDEVF
Ligand information
>8th5 Chain M (length=9) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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ALRITFGGP
Receptor-Ligand Complex Structure
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PDB
8th5
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
2.62 Å
Binding residue
(original residue number in PDB)
P6 V11 F15 F33 E117 A121 N122 K123 F124
Binding residue
(residue number reindexed from 1)
P2 V7 F11 F29 E104 A108 N109 K110 F111
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th5
,
PDBe:8th5
,
PDBj:8th5
PDBsum
8th5
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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