Structure of PDB 8syp Chain C Binding Site BS02

Receptor Information
>8syp Chain C (length=101) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
Q
Ligand information
>8syp Chain J (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccacatgccctgtgtctgcaagtacagaactagccagacagactgacct
atttttgtgaggggaatcgggaagtatccattgctaagactcagcaatgc
tgcaactctcagcaaccagctgaagatcagcagccgagaggccctgc
Receptor-Ligand Complex Structure
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PDB8syp Structural basis of cooperative targeting of the CX3CR1 nucleosome by PU.1 and C/EBPa
Resolution2.6 Å
Binding residue
(original residue number in PDB)		K13 R29 R42 V43 G44 A45 T76 R77
Binding residue
(residue number reindexed from 1)		K2 R18 R31 V32 G33 A34 T65 R66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8syp, PDBe:8syp, PDBj:8syp
PDBsum8syp
PubMed38267599
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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